姚静静,女,1993年8月生,博士,讲师,毕业于广州中医药大学。现就职于山西中医药大学太行本草研究院,研究方向为中药及活性成分抗心力衰竭的作用机制研究。主持山西省科技厅项目1项,发表SCI论文10余篇,其中第一作者4篇。
教育工作经历
2023.11-至今,山西中医药大学,讲师
2019.09-2022.06,广州中医药大学,中药学,博士
2016.09-2019.06,河南大学,药学,硕士
研究方向
中药及活性成分抗心力衰竭的作用机制研究
科研项目
[1]山西省科技厅基础研究计划青年项目,附子乌头类生物碱靶向Periostin抑制心肌纤维化治疗心力衰竭的作用机制研究,2024.07-2027.07,5万元,在研,主持。
[2]山西中医药大学博士科研启动基金,基于胞外基质蛋白介导的心肌纤维化探讨益气温阳法防治心力衰竭的作用机制研究,2024BK01,2024.05-2027.04,8万元,在研,主持。
代表性论文论著
[1]Yajuan Guo#,Jingjing Yao#, Zhenzhen Guo, Ming Ding, Kunlin Zhang, Qinghong Shen, Yu Li, Shaofang Yu, Ting Wan, Fuping Xu, Ying Wang, Xiaoxiao Qi, Jinjun Wu, Jianxin Chen*, Zhongqiu Liu*, Linlin Lu*. HBB contributes to individualized aconitine-induced cardiotoxicity in mice via interfering with ABHD5/AMPK/HDAC4 axis.Acta Pharmacologica Sinica. 2024;45(6):1224-1236.
[2]Jingjing Yao, Qinghong Shen, Min Huang, Ming Ding, Yajuan Guo, Wenbo Chen, Yuefang Lin, Yaqiu Zheng, Shaofang Yu, Wenxin Yan, Tao Su, Zhongqiu Liu*, Linlin Lu*. Screening tumor specificity targeted by arnicolide D, the active compound of Centipeda minima and molecular mechanism underlying by integrative pharmacology.Journal of Ethnopharmacology. 2022; 282:114583.
[3]Jingjing Yao, Min Huang, Qinghong Shen, Ming Ding, Shaofang Yu, Yajuan Guo, Yuefang Lin, Yaqiu Zheng, Wenbo Chen, Wenxin Yan, Zhongqiu Liu, Dawei Wang, Ming Hu*, Linlin Lu*. c-Myc-PD-L1 axis sustained gemcitabine-resistance in pancreatic cancer.Frontiers in Pharmacology. 2022;13:851512.
[4]Jingjing Yao, Zhenhua Du, Zibo Li, Shuhui Zhang, Yukun Lin, Haiyun Li, Lin Zhou, Yuehua Wang, Guixi Yan, Xianchuang Wu, Yongjian Duan, Gangjun Du*. 6-Gingerol as an arginase inhibitor prevents urethane-induced lung carcinogenesis by reprogramming tumor supporting M2 macrophages to M1 phenotype.Food Function. 2018; 9(9):4611-4620.
联系方式
办公地址:科研楼南108
邮箱:yaojingjing@sxtcm.edu.cn